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<meta name="DC.Title" content="Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility" />
<meta name="DC.Identifier" content="10.3174/ajnr.A3160" />
<meta name="DC.Date" content="2012-06-28" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: It is uncertain whether analgesic effects of vertebroplasty in patients with painful VCF are actually attributable to intervertebral cement infusion. This study aims to assess the validity of cement infusion performed for pain relief based on the presence or absence of pseudoarthrosis.

MATERIALS AND METHODS: We compared therapeutic effects between PVP and vertebral perforation without bone cement infusion in patients with painful VCF. The subjects were 64 patients undergoing PVP (PVP group) and 67 undergoing vertebral perforation (perforation group). In all patients, preoperative dynamic radiography was performed to assess the presence of vertebral mobility. Patients were classified into 2 groups, those with and those without vertebral mobility, and changes in VAS and ADL scores before and after surgery were compared between the PVP and perforation groups.

RESULTS: Regarding patients with vertebral mobility, VAS improved during the 3 months immediately after surgery in the PVP group compared with the perforation group ( P &lt; .05). Although no significant difference in postoperative ADL scores was observed between the 2 treatment groups, the scores 3 months after surgery were better in the PVP group than in the perforation group. Meanwhile, in the subgroup of patients without vertebral mobility, both treatments produced marked pain relief, but the difference was not significant ( P &gt; .05). Moreover, there was no difference in ADL scores between the 2 treatment groups.

CONCLUSIONS: Intervertebral cement infusion exerts analgesic effects in patients with VCF with pseudoarthrosis. However, in those without vertebral mobility, the analgesic effects of vertebroplasty are the same regardless of bone cement infusion.

### Abbreviations

ADL
:   activities of daily living
PVP
:   percutaneous vertebroplasty
STIR
:   short τ inversion recovery
VAS
:   visual analogue scale
VCF
:   vertebral compression fractures" />
<meta name="DC.Contributor" content="K. Yokoyama" />
<meta name="DC.Contributor" content="M. Kawanishi" />
<meta name="DC.Contributor" content="M. Yamada" />
<meta name="DC.Contributor" content="H. Tanaka" />
<meta name="DC.Contributor" content="Y. Ito" />
<meta name="DC.Contributor" content="M. Hirano" />
<meta name="DC.Contributor" content="T. Kuroiwa" />
<meta name="article:published_time" content="2012-06-28" />
<meta name="article:section" content="SPINE" />
<meta name="citation_title" content="Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;It is uncertain whether analgesic effects of vertebroplasty in patients with painful VCF are actually attributable to intervertebral cement infusion. This study aims to assess the validity of cement infusion performed for pain relief based on the presence or absence of pseudoarthrosis.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;We compared therapeutic effects between PVP and vertebral perforation without bone cement infusion in patients with painful VCF. The subjects were 64 patients undergoing PVP (PVP group) and 67 undergoing vertebral perforation (perforation group). In all patients, preoperative dynamic radiography was performed to assess the presence of vertebral mobility. Patients were classified into 2 groups, those with and those without vertebral mobility, and changes in VAS and ADL scores before and after surgery were compared between the PVP and perforation groups.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Regarding patients with vertebral mobility, VAS improved during the 3 months immediately after surgery in the PVP group compared with the perforation group (&lt;i&gt;P&lt;/i&gt; &amp;lt; .05). Although no significant difference in postoperative ADL scores was observed between the 2 treatment groups, the scores 3 months after surgery were better in the PVP group than in the perforation group. Meanwhile, in the subgroup of patients without vertebral mobility, both treatments produced marked pain relief, but the difference was not significant (&lt;i&gt;P&lt;/i&gt; &amp;gt; .05). Moreover, there was no difference in ADL scores between the 2 treatment groups.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;Intervertebral cement infusion exerts analgesic effects in patients with VCF with pseudoarthrosis. However, in those without vertebral mobility, the analgesic effects of vertebroplasty are the same regardless of bone cement infusion.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="K. Yokoyama" />
<meta name="citation_author" content="M. Kawanishi" />
<meta name="citation_author" content="M. Yamada" />
<meta name="citation_author" content="H. Tanaka" />
<meta name="citation_author" content="Y. Ito" />
<meta name="citation_author" content="M. Hirano" />
<meta name="citation_author" content="T. Kuroiwa" />
<meta name="twitter:title" content="Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility" />
<meta name="twitter:card" content="summary" />
<meta name="twitter:description" content="BACKGROUND AND PURPOSE: It is uncertain whether analgesic effects of vertebroplasty in patients with painful VCF are actually attributable to intervertebral cement infusion. This study aims to assess the validity of cement infusion performed for pain relief based on the presence or absence of pseudoarthrosis.

MATERIALS AND METHODS: We compared therapeutic effects between PVP and vertebral perforation without bone cement infusion in patients with painful VCF. The subjects were 64 patients undergoing PVP (PVP group) and 67 undergoing vertebral perforation (perforation group). In all patients, preoperative dynamic radiography was performed to assess the presence of vertebral mobility. Patients were classified into 2 groups, those with and those without vertebral mobility, and changes in VAS and ADL scores before and after surgery were compared between the PVP and perforation groups.

RESULTS: Regarding patients with vertebral mobility, VAS improved during the 3 months immediately after surgery in the PVP group compared with the perforation group ( P &lt; .05). Although no significant difference in postoperative ADL scores was observed between the 2 treatment groups, the scores 3 months after surgery were better in the PVP group than in the perforation group. Meanwhile, in the subgroup of patients without vertebral mobility, both treatments produced marked pain relief, but the difference was not significant ( P &gt; .05). Moreover, there was no difference in ADL scores between the 2 treatment groups.

CONCLUSIONS: Intervertebral cement infusion exerts analgesic effects in patients with VCF with pseudoarthrosis. However, in those without vertebral mobility, the analgesic effects of vertebroplasty are the same regardless of bone cement infusion.

### Abbreviations

ADL
:   activities of daily living
PVP
:   percutaneous vertebroplasty
STIR
:   short τ inversion recovery
VAS
:   visual analogue scale
VCF
:   vertebral compression fractures" />
<meta name="og-title" property="og:title" content="Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/early/2012/06/28/ajnr.A3160" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: It is uncertain whether analgesic effects of vertebroplasty in patients with painful VCF are actually attributable to intervertebral cement infusion. This study aims to assess the validity of cement infusion performed for pain relief based on the presence or absence of pseudoarthrosis.

MATERIALS AND METHODS: We compared therapeutic effects between PVP and vertebral perforation without bone cement infusion in patients with painful VCF. The subjects were 64 patients undergoing PVP (PVP group) and 67 undergoing vertebral perforation (perforation group). In all patients, preoperative dynamic radiography was performed to assess the presence of vertebral mobility. Patients were classified into 2 groups, those with and those without vertebral mobility, and changes in VAS and ADL scores before and after surgery were compared between the PVP and perforation groups.

RESULTS: Regarding patients with vertebral mobility, VAS improved during the 3 months immediately after surgery in the PVP group compared with the perforation group ( P &lt; .05). Although no significant difference in postoperative ADL scores was observed between the 2 treatment groups, the scores 3 months after surgery were better in the PVP group than in the perforation group. Meanwhile, in the subgroup of patients without vertebral mobility, both treatments produced marked pain relief, but the difference was not significant ( P &gt; .05). Moreover, there was no difference in ADL scores between the 2 treatment groups.

CONCLUSIONS: Intervertebral cement infusion exerts analgesic effects in patients with VCF with pseudoarthrosis. However, in those without vertebral mobility, the analgesic effects of vertebroplasty are the same regardless of bone cement infusion.

### Abbreviations

ADL
:   activities of daily living
PVP
:   percutaneous vertebroplasty
STIR
:   short τ inversion recovery
VAS
:   visual analogue scale
VCF
:   vertebral compression fractures" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node49813--7" data-node-nid="49813" id="top-node-49813--8880130577" data-pisa="ajnr;ajnr.A3160v1" data-pisa-master="ajnr;ajnr.A3160" data-apath="/ajnr/early/2012/06/28/ajnr.A3160.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
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      <h1 class="highwire-cite-title" id="page-title">Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">K. Yokoyama</span>, <span class="highwire-citation-author" data-delta="1">M. Kawanishi</span>, <span class="highwire-citation-author" data-delta="2">M. Yamada</span>, <span class="highwire-citation-author" data-delta="3">H. Tanaka</span>, <span class="highwire-citation-author" data-delta="4">Y. Ito</span>, <span class="highwire-citation-author" data-delta="5">M. Hirano</span> and <span class="highwire-citation-author" data-delta="6">T. Kuroiwa</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">June 2012,  </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A3160 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-49813--8880130577" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">K. Yokoyama </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=K.%2BYokoyama%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Yokoyama%20K&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AK.%2BYokoyama%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">M. 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Tanaka </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=H.%2BTanaka%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Tanaka%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AH.%2BTanaka%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">Y. Ito </div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Y.%2BIto%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Ito%20Y&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AY.%2BIto%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">M. 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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div xmlns:xhtml="http://www.w3.org/1999/xhtml" class="contributors"><ol class="contributor-list" id="contrib-group-1"><li class="contributor" id="contrib-1"><span class="name">K. Yokoyama</span><a id="xref-aff-1-1" class="xref-aff" href="#aff-1"></a>, </li><li class="contributor" id="contrib-2"><span class="name">M. Kawanishi</span><a id="xref-aff-1-2" class="xref-aff" href="#aff-1"></a>, </li><li class="contributor" id="contrib-3"><span class="name">M. Yamada</span><a id="xref-aff-1-3" class="xref-aff" href="#aff-1"></a>, </li><li class="contributor" id="contrib-4"><span class="name">H. Tanaka</span><a id="xref-aff-1-4" class="xref-aff" href="#aff-1"></a>, </li><li class="contributor" id="contrib-5"><span class="name">Y. Ito</span><a id="xref-aff-1-5" class="xref-aff" href="#aff-1"></a>, </li><li class="contributor" id="contrib-6"><span class="name">M. Hirano</span><a id="xref-aff-1-6" class="xref-aff" href="#aff-1"></a> and </li><li class="last" id="contrib-7"><span class="name">T. Kuroiwa</span><a id="xref-aff-1-7" class="xref-aff" href="#aff-1"></a></li></ol><ol class="affiliation-list"><li class="aff"><a id="aff-1" name="aff-1"></a><address>From the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto; and Departments of Neurosurgery and Surgical Pathology (T.K.), Osaka Medical College, Takatsuki, Osaka, Japan.</address></li></ol><ol class="corresp-list"><li class="corresp" id="corresp-1">Please address correspondence to Kunio Yokoyama, Department of Neurosurgery, Takeda General Hospital, 28-21, Ishidamoriminami-machi, Fushimi, Kyoto City, Kyoto 601-1495, Japan; e-mail: <span class="em-link"><span class="em-addr">neu100{at}poh.osaka-med.ac.jp</span></span></li></ol></div></div></div>  </div>

  
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