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<meta name="HW.identifier" content="/ajnr/early/2015/03/19/ajnr.A4282.atom" />
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<meta name="DC.Title" content="Endovascular Treatment of Wide-Neck Anterior Communicating Artery Aneurysms Using WEB-DL and WEB-SL: Short-Term Results in a Multicenter Study" />
<meta name="DC.Identifier" content="10.3174/ajnr.A4282" />
<meta name="DC.Date" content="2015-03-19" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
<meta name="DC.Rights" content="© 2015 American Society of Neuroradiology" />
<meta name="DC.AccessRights" content="restricted" />
<meta name="DC.Description" content="BACKGROUND AND PURPOSE: Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.

MATERIALS AND METHODS: Patients with anterior communicating artery aneurysms treated with the WEB device between June 2013 and March 2014 in 5 French centers were analyzed. Procedural success, technical complications, clinical outcome at 1 month, and immediate and 3- to 6-month angiographic follow-up results were analyzed.

RESULTS: Ten patients with unruptured anterior communicating artery aneurysms with a mean neck diameter of 5.4 mm were treated with the WEB. Treatment failed in 3 of the 10 aneurysms without further clinical complications. One patient developed a procedural thromboembolic event, and the other 6 had normal neurologic examination findings at 1-month follow-up. Immediate anatomic outcome evaluation showed adequate occlusion (total occlusion or neck remnant) in 6 of 7 patients. Angiographic control was obtained in all patients, including 6 adequate aneurysm occlusions (3 complete occlusions and 3 neck remnants) at short-term follow-up.

CONCLUSIONS: In our small series, treatment of wide-neck anterior communicating artery aneurysms with the WEB device was feasible and safe. However, patient selection based on the aneurysm and initial angiographic findings in the parent artery is important due to the limitations of the WEB device navigation.

### Abbreviations

WEB
:   Woven EndoBridge
WEB-DL
:   WEB Dual-Layer
WEB-SL
:   WEB Single-Layer" />
<meta name="DC.Contributor" content="D.N. Gherasim" />
<meta name="DC.Contributor" content="B. Gory" />
<meta name="DC.Contributor" content="R. Sivan-Hoffmann" />
<meta name="DC.Contributor" content="L. Pierot" />
<meta name="DC.Contributor" content="H. Raoult" />
<meta name="DC.Contributor" content="J.-Y. Gauvrit" />
<meta name="DC.Contributor" content="H. Desal" />
<meta name="DC.Contributor" content="X. Barreau" />
<meta name="DC.Contributor" content="D. Herbreteau" />
<meta name="DC.Contributor" content="R. Riva" />
<meta name="DC.Contributor" content="F. Ambesi Impiombato" />
<meta name="DC.Contributor" content="X. Armoiry" />
<meta name="DC.Contributor" content="F. Turjman" />
<meta name="article:published_time" content="2015-03-19" />
<meta name="article:section" content="INTERVENTIONAL" />
<meta name="citation_title" content="Endovascular Treatment of Wide-Neck Anterior Communicating Artery Aneurysms Using WEB-DL and WEB-SL: Short-Term Results in a Multicenter Study" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;Patients with anterior communicating artery aneurysms treated with the WEB device between June 2013 and March 2014 in 5 French centers were analyzed. Procedural success, technical complications, clinical outcome at 1 month, and immediate and 3- to 6-month angiographic follow-up results were analyzed.&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;Ten patients with unruptured anterior communicating artery aneurysms with a mean neck diameter of 5.4 mm were treated with the WEB. Treatment failed in 3 of the 10 aneurysms without further clinical complications. One patient developed a procedural thromboembolic event, and the other 6 had normal neurologic examination findings at 1-month follow-up. Immediate anatomic outcome evaluation showed adequate occlusion (total occlusion or neck remnant) in 6 of 7 patients. Angiographic control was obtained in all patients, including 6 adequate aneurysm occlusions (3 complete occlusions and 3 neck remnants) at short-term follow-up.&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;In our small series, treatment of wide-neck anterior communicating artery aneurysms with the WEB device was feasible and safe. However, patient selection based on the aneurysm and initial angiographic findings in the parent artery is important due to the limitations of the WEB device navigation.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
<meta name="citation_publisher" content="American Journal of Neuroradiology" />
<meta name="citation_publication_date" content="2015/03/19" />
<meta name="citation_mjid" content="ajnr;ajnr.A4282v1" />
<meta name="citation_id" content="ajnr.A4282v1" />
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<meta name="citation_issn" content="0195-6108" />
<meta name="citation_issn" content="1936-959X" />
<meta name="citation_doi" content="10.3174/ajnr.A4282" />
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<meta name="citation_article_type" content="Research Article" />
<meta name="citation_section" content="INTERVENTIONAL" />
<meta name="citation_author" content="D.N. Gherasim" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="B. Gory" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="R. Sivan-Hoffmann" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="L. Pierot" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="H. Raoult" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="J.-Y. Gauvrit" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="H. Desal" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="X. Barreau" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="D. Herbreteau" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="R. Riva" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="F. Ambesi Impiombato" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="X. Armoiry" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="citation_author" content="F. Turjman" />
<meta name="citation_author_institution" content="From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France." />
<meta name="twitter:title" content="Endovascular Treatment of Wide-Neck Anterior Communicating Artery Aneurysms Using WEB-DL and WEB-SL: Short-Term Results in a Multicenter Study" />
<meta name="twitter:card" content="summary" />
<meta name="twitter:description" content="BACKGROUND AND PURPOSE: Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.

MATERIALS AND METHODS: Patients with anterior communicating artery aneurysms treated with the WEB device between June 2013 and March 2014 in 5 French centers were analyzed. Procedural success, technical complications, clinical outcome at 1 month, and immediate and 3- to 6-month angiographic follow-up results were analyzed.

RESULTS: Ten patients with unruptured anterior communicating artery aneurysms with a mean neck diameter of 5.4 mm were treated with the WEB. Treatment failed in 3 of the 10 aneurysms without further clinical complications. One patient developed a procedural thromboembolic event, and the other 6 had normal neurologic examination findings at 1-month follow-up. Immediate anatomic outcome evaluation showed adequate occlusion (total occlusion or neck remnant) in 6 of 7 patients. Angiographic control was obtained in all patients, including 6 adequate aneurysm occlusions (3 complete occlusions and 3 neck remnants) at short-term follow-up.

CONCLUSIONS: In our small series, treatment of wide-neck anterior communicating artery aneurysms with the WEB device was feasible and safe. However, patient selection based on the aneurysm and initial angiographic findings in the parent artery is important due to the limitations of the WEB device navigation.

### Abbreviations

WEB
:   Woven EndoBridge
WEB-DL
:   WEB Dual-Layer
WEB-SL
:   WEB Single-Layer" />
<meta name="og-title" property="og:title" content="Endovascular Treatment of Wide-Neck Anterior Communicating Artery Aneurysms Using WEB-DL and WEB-SL: Short-Term Results in a Multicenter Study" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/early/2015/03/19/ajnr.A4282" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.

MATERIALS AND METHODS: Patients with anterior communicating artery aneurysms treated with the WEB device between June 2013 and March 2014 in 5 French centers were analyzed. Procedural success, technical complications, clinical outcome at 1 month, and immediate and 3- to 6-month angiographic follow-up results were analyzed.

RESULTS: Ten patients with unruptured anterior communicating artery aneurysms with a mean neck diameter of 5.4 mm were treated with the WEB. Treatment failed in 3 of the 10 aneurysms without further clinical complications. One patient developed a procedural thromboembolic event, and the other 6 had normal neurologic examination findings at 1-month follow-up. Immediate anatomic outcome evaluation showed adequate occlusion (total occlusion or neck remnant) in 6 of 7 patients. Angiographic control was obtained in all patients, including 6 adequate aneurysm occlusions (3 complete occlusions and 3 neck remnants) at short-term follow-up.

CONCLUSIONS: In our small series, treatment of wide-neck anterior communicating artery aneurysms with the WEB device was feasible and safe. However, patient selection based on the aneurysm and initial angiographic findings in the parent artery is important due to the limitations of the WEB device navigation.

### Abbreviations

WEB
:   Woven EndoBridge
WEB-DL
:   WEB Dual-Layer
WEB-SL
:   WEB Single-Layer" />
<meta name="og-type" property="og:type" content="article" />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node51001--5" data-node-nid="51001" id="top-node-51001--6206169149" data-pisa="ajnr;ajnr.A4282v1" data-pisa-master="ajnr;ajnr.A4282" data-apath="/ajnr/early/2015/03/19/ajnr.A4282.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
      <div class="highwire-cite-overline"><span  class="highwire-cite-metadata-article-type highwire-cite-metadata">Research Article</span><span class="separator-pipe"></span><span  class="highwire-cite-metadata-art-cat highwire-cite-metadata"><span class="wrapper">INTERVENTIONAL</span></span></div>
  
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      <h1 class="highwire-cite-title" id="page-title">Endovascular Treatment of Wide-Neck Anterior Communicating Artery Aneurysms Using WEB-DL and WEB-SL: Short-Term Results in a Multicenter Study</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">D.N. Gherasim</span>, <span class="highwire-citation-author" data-delta="1">B. Gory</span>, <span class="highwire-citation-author" data-delta="2">R. Sivan-Hoffmann</span>, <span class="highwire-citation-author" data-delta="3">L. Pierot</span>, <span class="highwire-citation-author" data-delta="4">H. Raoult</span>, <span class="highwire-citation-author" data-delta="5">J.-Y. Gauvrit</span>, <span class="highwire-citation-author" data-delta="6">H. Desal</span>, <span class="highwire-citation-author" data-delta="7">X. Barreau</span>, <span class="highwire-citation-author" data-delta="8">D. Herbreteau</span>, <span class="highwire-citation-author" data-delta="9">R. Riva</span>, <span class="highwire-citation-author" data-delta="10">F. Ambesi Impiombato</span>, <span class="highwire-citation-author" data-delta="11">X. Armoiry</span> and <span class="highwire-citation-author" data-delta="12">F. Turjman</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">March 2015,  </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A4282 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-51001--6206169149" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">D.N. Gherasim </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=D.N.%2BGherasim%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gherasim%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AD.N.%2BGherasim%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">B. Gory </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=B.%2BGory%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gory%20B&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AB.%2BGory%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">R. Sivan-Hoffmann </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=R.%2BSivan-Hoffmann%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Sivan-Hoffmann%20R&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AR.%2BSivan-Hoffmann%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">L. Pierot </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=L.%2BPierot%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Pierot%20L&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AL.%2BPierot%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">H. Raoult </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=H.%2BRaoult%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Raoult%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AH.%2BRaoult%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-5"><div class="author-tooltip-name">J.-Y. Gauvrit </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.-Y.%2BGauvrit%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gauvrit%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AJ.-Y.%2BGauvrit%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-6"><div class="author-tooltip-name">H. Desal </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=H.%2BDesal%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Desal%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AH.%2BDesal%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-7"><div class="author-tooltip-name">X. Barreau </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=X.%2BBarreau%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Barreau%20X&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AX.%2BBarreau%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-8"><div class="author-tooltip-name">D. Herbreteau </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the Department of Interventional Neuroradiology (D.N.G., B.G., R.S.-H., F.A.I., R.R., F.T.) and Direction de la Recherche Clinique et de l'Innovation (X.A.), Hôpital Neurologique Pierre Wertheimer, Hospices Civils de Lyon, Lyon, France; Department of Radiology (L.P.), Hôpital Maison Blanche, Reims, France; Department of Neuroradiology (H.R., J.-Y.G), Centre Hospitalier Universitaire Rennes, Rennes, France; Department of Neuroradiology (H.D.), Centre Hospitalier Universitaire Nantes, Nantes, France; Department of Neuroradiology (X.B.), Pellegrin Hospital, Bordeaux, France; and Department of Neuroradiology (D.H.), Centre Hospitalier Universitaire Tours, Tours, France.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=D.%2BHerbreteau%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Herbreteau%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AD.%2BHerbreteau%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-9"><div class="author-tooltip-name">R. 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<p id="p-2"><strong>BACKGROUND AND PURPOSE:</strong> Endovascular treatment of wide-neck anterior communicating artery aneurysms can often be challenging. The Woven EndoBridge (WEB) device is a recently developed intrasaccular flow disrupter dedicated to endovascular treatment of intracranial aneurysms. The aim of this study was to investigate the feasibility, safety, and efficacy of the WEB Dual-Layer and WEB Single-Layer devices for the treatment of wide-neck anterior communicating artery aneurysms.</p></div>
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<p id="p-3"><strong>MATERIALS AND METHODS:</strong> Patients with anterior communicating artery aneurysms treated with the WEB device between June 2013 and March 2014 in 5 French centers were analyzed. Procedural success, technical complications, clinical outcome at 1 month, and immediate and 3- to 6-month angiographic follow-up results were analyzed.</p></div>
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<p id="p-4"><strong>RESULTS:</strong> Ten patients with unruptured anterior communicating artery aneurysms with a mean neck diameter of 5.4 mm were treated with the WEB. Treatment failed in 3 of the 10 aneurysms without further clinical complications. One patient developed a procedural thromboembolic event, and the other 6 had normal neurologic examination findings at 1-month follow-up. Immediate anatomic outcome evaluation showed adequate occlusion (total occlusion or neck remnant) in 6 of 7 patients. Angiographic control was obtained in all patients, including 6 adequate aneurysm occlusions (3 complete occlusions and 3 neck remnants) at short-term follow-up.</p></div>
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<p id="p-5"><strong>CONCLUSIONS:</strong> In our small series, treatment of wide-neck anterior communicating artery aneurysms with the WEB device was feasible and safe. However, patient selection based on the aneurysm and initial angiographic findings in the parent artery is important due to the limitations of the WEB device navigation.</p>
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<h3>Abbreviations</h3>
<dl id="def-list-1"><dt id="def-item-1">WEB<span class="def-item-dt-sep"></span></dt><dd>Woven EndoBridge<span class="def-item-dd-sep"></span></dd><dt id="def-item-2">WEB-DL<span class="def-item-dt-sep"></span></dt><dd>WEB Dual-Layer<span class="def-item-dd-sep"></span></dd><dt id="def-item-3">WEB-SL<span class="def-item-dt-sep"></span></dt><dd>WEB Single-Layer</dd></dl>
</div><div class="section fn-group" id="fn-group-1"><h2>Footnotes</h2><ul><li class="fn-equal" id="fn-1">
<p id="p-1">D.N.G. and B.G. contributed equally to this work.</p></li></ul></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">© 2015 American Society of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div>  </div>

  
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