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<meta name="DC.Title" content="Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly" />
<meta name="DC.Identifier" content="10.3174/ajnr.A8473" />
<meta name="DC.Date" content="2024-08-27" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="BACKGROUND AND PURPOSE: The efficacy and safety of endovascular thrombectomy (EVT) for elderly basilar artery occlusion (BAO) stroke patients is unclear.

MATERIALS AND METHODS: This was an explorative retrospective analysis of the 2016-21 National Inpatient Sample in the United States. Elderly BAO stroke patients (80 years or older) with NIH stroke scale of at least 5 were included. Primary outcome was discharge to home. Secondary outcomes include in-hospital mortality and intracranial hemorrhage (ICH). Outcomes were compared between patients treated with EVT and those treated with medical management (MM) alone. Propensity score matching (PSM) was performed to control for confounders. Subgroup analyses were conducted for patients who did and did not receive intravenous thrombolysis (IVT).

RESULTS: 2,520 elderly BAO patients were identified; 830 received EVT, and 1,690 received MM alone. After PSM, 1,115 patients and 715 patients remained in the MM and EVT groups, respectively. Compared to PSM controls, EVT was not significantly associated with different rates of home discharge (17.5% vs. 12.2%, OR 1.36 [95%CI 0.76-2.44], p=0.30) or in-hospital mortality (31.5% vs. 32.9%, OR 1.00 [95%CI 0.63-1.60], p=0.99), but it was significantly associated with higher rates of ICH (18.2% vs. 7.3%, OR 2.69 [95%CI 1.41- 5.15], p=0.003). Among patients who did not receive IVT, EVT was significantly associated with higher rates of home discharge (21.5% vs. 11.5%, OR 1.93 [95%CI 1.02-3.66], p=0.044), whereas EVT was not significantly associated with the same among those treated with IVT (5.6% vs. 15.0%, OR 0.28 [95%CI 0.05-1.46], p=0.13). Interaction analysis revealed that IVT was a negative modulator of EVT’s positive association with home discharge (interaction p=0.031).

CONCLUSIONS: EVT was not significantly associated with more favorable hospitalization outcomes for elderly BAO stroke patients, and it was significantly associated with increased risk of ICH. EVT may be an effective treatment for patients who did not receive IVT.

ABBREVIATIONS: EVT = endovascular thrombectomy; BAO = basilar artery occlusion; ICH = intracranial hemorrhage; MM = medical management; PSM = propensity score matching; IVT = intravenous thrombolysis." />
<meta name="DC.Contributor" content="Huanwen Chen" />
<meta name="DC.Contributor" content="Marco Colasurdo" />
<meta name="DC.Contributor" content="Mihir Khunte" />
<meta name="DC.Contributor" content="Ajay Malhotra" />
<meta name="DC.Contributor" content="Dheeraj Gandhi" />
<meta name="article:published_time" content="2024-08-26" />
<meta name="article:section" content="ORIGINAL RESEARCH" />
<meta name="citation_title" content="Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly" />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;ABSTRACT&lt;/h3&gt;
&lt;h3&gt;BACKGROUND AND PURPOSE:&lt;/h3&gt;
&lt;p&gt;The efficacy and safety of endovascular thrombectomy (EVT) for elderly basilar artery occlusion (BAO) stroke patients is unclear.&lt;/p&gt;&lt;h3&gt;MATERIALS AND METHODS:&lt;/h3&gt;
&lt;p&gt;This was an explorative retrospective analysis of the 2016-21 National Inpatient Sample in the United States. Elderly BAO stroke patients (80 years or older) with NIH stroke scale of at least 5 were included. Primary outcome was discharge to home. Secondary outcomes include in-hospital mortality and intracranial hemorrhage (ICH). Outcomes were compared between patients treated with EVT and those treated with medical management (MM) alone. Propensity score matching (PSM) was performed to control for confounders. Subgroup analyses were conducted for patients who did and did not receive intravenous thrombolysis (IVT).&lt;/p&gt;&lt;h3&gt;RESULTS:&lt;/h3&gt;
&lt;p&gt;2,520 elderly BAO patients were identified; 830 received EVT, and 1,690 received MM alone. After PSM, 1,115 patients and 715 patients remained in the MM and EVT groups, respectively. Compared to PSM controls, EVT was not significantly associated with different rates of home discharge (17.5% vs. 12.2%, OR 1.36 [95%CI 0.76-2.44], p=0.30) or in-hospital mortality (31.5% vs. 32.9%, OR 1.00 [95%CI 0.63-1.60], p=0.99), but it was significantly associated with higher rates of ICH (18.2% vs. 7.3%, OR 2.69 [95%CI 1.41- 5.15], p=0.003). Among patients who did not receive IVT, EVT was significantly associated with higher rates of home discharge (21.5% vs. 11.5%, OR 1.93 [95%CI 1.02-3.66], p=0.044), whereas EVT was not significantly associated with the same among those treated with IVT (5.6% vs. 15.0%, OR 0.28 [95%CI 0.05-1.46], p=0.13). Interaction analysis revealed that IVT was a negative modulator of EVT’s positive association with home discharge (interaction p=0.031).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS:&lt;/h3&gt;
&lt;p&gt;EVT was not significantly associated with more favorable hospitalization outcomes for elderly BAO stroke patients, and it was significantly associated with increased risk of ICH. EVT may be an effective treatment for patients who did not receive IVT.&lt;/p&gt;&lt;p&gt;ABBREVIATIONS: EVT = endovascular thrombectomy; BAO = basilar artery occlusion; ICH = intracranial hemorrhage; MM = medical management; PSM = propensity score matching; IVT = intravenous thrombolysis.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
<meta name="citation_publisher" content="American Journal of Neuroradiology" />
<meta name="citation_publication_date" content="2024/08/26" />
<meta name="citation_mjid" content="ajnr;ajnr.A8473v2" />
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<meta name="citation_article_type" content="Research Article" />
<meta name="citation_section" content="ORIGINAL RESEARCH" />
<meta name="citation_author" content="Huanwen Chen" />
<meta name="citation_author_institution" content="From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health &amp; Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA." />
<meta name="citation_author" content="Marco Colasurdo" />
<meta name="citation_author_institution" content="From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health &amp; Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA." />
<meta name="citation_author" content="Mihir Khunte" />
<meta name="citation_author_institution" content="From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health &amp; Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA." />
<meta name="citation_author" content="Ajay Malhotra" />
<meta name="citation_author_institution" content="From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health &amp; Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA." />
<meta name="citation_author" content="Dheeraj Gandhi" />
<meta name="citation_author_institution" content="From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health &amp; Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA." />
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<meta name="twitter:description" content="BACKGROUND AND PURPOSE: The efficacy and safety of endovascular thrombectomy (EVT) for elderly basilar artery occlusion (BAO) stroke patients is unclear.

MATERIALS AND METHODS: This was an explorative retrospective analysis of the 2016-21 National Inpatient Sample in the United States. Elderly BAO stroke patients (80 years or older) with NIH stroke scale of at least 5 were included. Primary outcome was discharge to home. Secondary outcomes include in-hospital mortality and intracranial hemorrhage (ICH). Outcomes were compared between patients treated with EVT and those treated with medical management (MM) alone. Propensity score matching (PSM) was performed to control for confounders. Subgroup analyses were conducted for patients who did and did not receive intravenous thrombolysis (IVT).

RESULTS: 2,520 elderly BAO patients were identified; 830 received EVT, and 1,690 received MM alone. After PSM, 1,115 patients and 715 patients remained in the MM and EVT groups, respectively. Compared to PSM controls, EVT was not significantly associated with different rates of home discharge (17.5% vs. 12.2%, OR 1.36 [95%CI 0.76-2.44], p=0.30) or in-hospital mortality (31.5% vs. 32.9%, OR 1.00 [95%CI 0.63-1.60], p=0.99), but it was significantly associated with higher rates of ICH (18.2% vs. 7.3%, OR 2.69 [95%CI 1.41- 5.15], p=0.003). Among patients who did not receive IVT, EVT was significantly associated with higher rates of home discharge (21.5% vs. 11.5%, OR 1.93 [95%CI 1.02-3.66], p=0.044), whereas EVT was not significantly associated with the same among those treated with IVT (5.6% vs. 15.0%, OR 0.28 [95%CI 0.05-1.46], p=0.13). Interaction analysis revealed that IVT was a negative modulator of EVT’s positive association with home discharge (interaction p=0.031).

CONCLUSIONS: EVT was not significantly associated with more favorable hospitalization outcomes for elderly BAO stroke patients, and it was significantly associated with increased risk of ICH. EVT may be an effective treatment for patients who did not receive IVT.

ABBREVIATIONS: EVT = endovascular thrombectomy; BAO = basilar artery occlusion; ICH = intracranial hemorrhage; MM = medical management; PSM = propensity score matching; IVT = intravenous thrombolysis." />
<meta name="og-title" property="og:title" content="Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly" />
<meta name="og-url" property="og:url" content="http://ajnr-stage2.stage.highwire.org/content/early/2024/08/27/ajnr.A8473" />
<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="BACKGROUND AND PURPOSE: The efficacy and safety of endovascular thrombectomy (EVT) for elderly basilar artery occlusion (BAO) stroke patients is unclear.

MATERIALS AND METHODS: This was an explorative retrospective analysis of the 2016-21 National Inpatient Sample in the United States. Elderly BAO stroke patients (80 years or older) with NIH stroke scale of at least 5 were included. Primary outcome was discharge to home. Secondary outcomes include in-hospital mortality and intracranial hemorrhage (ICH). Outcomes were compared between patients treated with EVT and those treated with medical management (MM) alone. Propensity score matching (PSM) was performed to control for confounders. Subgroup analyses were conducted for patients who did and did not receive intravenous thrombolysis (IVT).

RESULTS: 2,520 elderly BAO patients were identified; 830 received EVT, and 1,690 received MM alone. After PSM, 1,115 patients and 715 patients remained in the MM and EVT groups, respectively. Compared to PSM controls, EVT was not significantly associated with different rates of home discharge (17.5% vs. 12.2%, OR 1.36 [95%CI 0.76-2.44], p=0.30) or in-hospital mortality (31.5% vs. 32.9%, OR 1.00 [95%CI 0.63-1.60], p=0.99), but it was significantly associated with higher rates of ICH (18.2% vs. 7.3%, OR 2.69 [95%CI 1.41- 5.15], p=0.003). Among patients who did not receive IVT, EVT was significantly associated with higher rates of home discharge (21.5% vs. 11.5%, OR 1.93 [95%CI 1.02-3.66], p=0.044), whereas EVT was not significantly associated with the same among those treated with IVT (5.6% vs. 15.0%, OR 0.28 [95%CI 0.05-1.46], p=0.13). Interaction analysis revealed that IVT was a negative modulator of EVT’s positive association with home discharge (interaction p=0.031).

CONCLUSIONS: EVT was not significantly associated with more favorable hospitalization outcomes for elderly BAO stroke patients, and it was significantly associated with increased risk of ICH. EVT may be an effective treatment for patients who did not receive IVT.

ABBREVIATIONS: EVT = endovascular thrombectomy; BAO = basilar artery occlusion; ICH = intracranial hemorrhage; MM = medical management; PSM = propensity score matching; IVT = intravenous thrombolysis." />
<meta name="og-type" property="og:type" content="article" />
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">Huanwen Chen</span>, <span class="highwire-citation-author" data-delta="1">Marco Colasurdo</span>, <span class="highwire-citation-author" data-delta="2">Mihir Khunte</span>, <span class="highwire-citation-author" data-delta="3">Ajay Malhotra</span> and <span class="highwire-citation-author" data-delta="4">Dheeraj Gandhi</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">August 2024,  </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">ajnr.A8473; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A8473 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-110072--61003974288" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">Huanwen Chen </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health & Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Huanwen%2BChen%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Chen%20H&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AHuanwen%2BChen%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">Marco Colasurdo </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health & Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Marco%2BColasurdo%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Colasurdo%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMarco%2BColasurdo%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">Mihir Khunte </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health & Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Mihir%2BKhunte%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Khunte%20M&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AMihir%2BKhunte%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">Ajay Malhotra </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health & Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Ajay%2BMalhotra%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Malhotra%20A&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AAjay%2BMalhotra%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-4"><div class="author-tooltip-name">Dheeraj Gandhi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>From the National Institute of Neurological Disorders and Stroke (H.C.), National Institute of Health, Bethesda MD, USA; Department of Interventional Radiology (M.C.), Oregon Health & Science University, Portland OR, USA; Warren Alpert Medical School (M.K.), Brown University, Providence RI, USA; Department of Radiology (A.M.), Yale New Haven Hospital, New Haven CT, USA; Departments of Neurosurgery, Radiology and Neurology (D.G.), University of Maryland Medical Center, Baltimore MD, USA.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=Dheeraj%2BGandhi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Gandhi%20D&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3ADheeraj%2BGandhi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div></div></div>  </div>

  
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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" data-highwire-cite-ref-tooltip-instance="highwire_reflinks_tooltip" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div class="article abstract-view "><span class="highwire-journal-article-marker-start"></span><div class="section abstract" id="abstract-1"><h2 class="">ABSTRACT</h2><div id="sec-1" class="subsection"><p id="p-1"><strong>BACKGROUND AND PURPOSE:</strong> The efficacy and safety of endovascular thrombectomy (EVT) for elderly basilar artery occlusion (BAO) stroke patients is unclear.</p></div><div id="sec-2" class="subsection"><p id="p-2"><strong>MATERIALS AND METHODS:</strong> This was an explorative retrospective analysis of the 2016-21 National Inpatient Sample in the United States. Elderly BAO stroke patients (80 years or older) with NIH stroke scale of at least 5 were included. Primary outcome was discharge to home. Secondary outcomes include in-hospital mortality and intracranial hemorrhage (ICH). Outcomes were compared between patients treated with EVT and those treated with medical management (MM) alone. Propensity score matching (PSM) was performed to control for confounders. Subgroup analyses were conducted for patients who did and did not receive intravenous thrombolysis (IVT).</p></div><div id="sec-3" class="subsection"><p id="p-3"><strong>RESULTS:</strong> 2,520 elderly BAO patients were identified; 830 received EVT, and 1,690 received MM alone. After PSM, 1,115 patients and 715 patients remained in the MM and EVT groups, respectively. Compared to PSM controls, EVT was not significantly associated with different rates of home discharge (17.5% vs. 12.2%, OR 1.36 [95%CI 0.76-2.44], p=0.30) or in-hospital mortality (31.5% vs. 32.9%, OR 1.00 [95%CI 0.63-1.60], p=0.99), but it was significantly associated with higher rates of ICH (18.2% vs. 7.3%, OR 2.69 [95%CI 1.41- 5.15], p=0.003). Among patients who did not receive IVT, EVT was significantly associated with higher rates of home discharge (21.5% vs. 11.5%, OR 1.93 [95%CI 1.02-3.66], p=0.044), whereas EVT was not significantly associated with the same among those treated with IVT (5.6% vs. 15.0%, OR 0.28 [95%CI 0.05-1.46], p=0.13). Interaction analysis revealed that IVT was a negative modulator of EVT’s positive association with home discharge (interaction p=0.031).</p></div><div id="sec-4" class="subsection"><p id="p-4"><strong>CONCLUSIONS:</strong> EVT was not significantly associated with more favorable hospitalization outcomes for elderly BAO stroke patients, and it was significantly associated with increased risk of ICH. EVT may be an effective treatment for patients who did not receive IVT.</p><p id="p-5">ABBREVIATIONS: EVT = endovascular thrombectomy; BAO = basilar artery occlusion; ICH = intracranial hemorrhage; MM = medical management; PSM = propensity score matching; IVT = intravenous thrombolysis.</p></div></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">© 2024 by American Journal of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div>  </div>

  
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      <div class="highwire-cite-title">Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Huanwen</span> <span class="nlm-surname">Chen</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Marco</span> <span class="nlm-surname">Colasurdo</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Mihir</span> <span class="nlm-surname">Khunte</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Ajay</span> <span class="nlm-surname">Malhotra</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Dheeraj</span> <span class="nlm-surname">Gandhi</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2024, </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">ajnr.A8473; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8473 </span></div>
  
  
  
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      <div class="highwire-cite-title">Endovascular thrombectomy versus medical management for acute basilar artery occlusion stroke in the elderly</div>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">Huanwen</span> <span class="nlm-surname">Chen</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">Marco</span> <span class="nlm-surname">Colasurdo</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">Mihir</span> <span class="nlm-surname">Khunte</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">Ajay</span> <span class="nlm-surname">Malhotra</span></span>, <span class="highwire-citation-author" data-delta="4"><span class="nlm-given-names">Dheeraj</span> <span class="nlm-surname">Gandhi</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Aug 2024, </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">ajnr.A8473; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A8473 </span></div>
  
  
  
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