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<meta name="DC.Title" content="MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences." />
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<meta name="DC.Description" content="PURPOSE AND METHODS High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years.

FINDINGS For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009).

CONCLUSIONS This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders." />
<meta name="DC.Contributor" content="P M Doraiswamy" />
<meta name="DC.Contributor" content="J M Potts" />
<meta name="DC.Contributor" content="D A Axelson" />
<meta name="DC.Contributor" content="M M Husain" />
<meta name="DC.Contributor" content="S N Lurie" />
<meta name="DC.Contributor" content="C Na" />
<meta name="DC.Contributor" content="P R Escalona" />
<meta name="DC.Contributor" content="W M McDonald" />
<meta name="DC.Contributor" content="G S Figiel" />
<meta name="DC.Contributor" content="E H Ellinwood" />
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<meta name="citation_title" content="MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE AND METHODS&lt;/h3&gt;
&lt;p&gt;High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years.&lt;/p&gt;&lt;h3&gt;FINDINGS&lt;/h3&gt;
&lt;p&gt;For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS&lt;/h3&gt;
&lt;p&gt;This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders.&lt;/p&gt;" />
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<meta name="twitter:description" content="PURPOSE AND METHODS High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years.

FINDINGS For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009).

CONCLUSIONS This study confirms that aging is accompanied by gender-specific changes in pituitary size and shape, and provides normative data that may facilitate evaluation of the pituitary gland in neuroendocrine disorders." />
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<meta name="og-description" property="og:description" content="PURPOSE AND METHODS High-field MR images at 1.5 T were used to characterize the effects of age and gender on pituitary size and shape in a sample of 71 adult volunteers (40 females), aged 21 to 82 years.

FINDINGS For all subjects, age was inversely correlated with pituitary height (r = -.43, P less than .0002) and cross-sectional area (r = -.35, P less than .0028). Age-specific gender differences were also present in pituitary height and area. A convex upper pituitary margin was more common in females (P = .002) and younger subjects (P = .009).

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      <h1 class="highwire-cite-title" id="page-title">MR assessment of pituitary gland morphology in healthy volunteers: age- and gender-related differences.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">P M Doraiswamy</span>, <span class="highwire-citation-author" data-delta="1">J M Potts</span>, <span class="highwire-citation-author" data-delta="2">D A Axelson</span>, <span class="highwire-citation-author" data-delta="3">M M Husain</span>, <span class="highwire-citation-author" data-delta="4">S N Lurie</span>, <span class="highwire-citation-author" data-delta="5">C Na</span>, <span class="highwire-citation-author" data-delta="6">P R Escalona</span>, <span class="highwire-citation-author" data-delta="7">W M McDonald</span>, <span class="highwire-citation-author" data-delta="8">G S Figiel</span> and <span class="highwire-citation-author" data-delta="9">E H Ellinwood</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">September 1992,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">13 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(5) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1295-1299; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-5503--62112719123" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">P M Doraiswamy </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Psychiatry, Duke University Medical Center, Durham, NC 27710.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=P%2BM%2BDoraiswamy%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Doraiswamy%20PM&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AP%2BM%2BDoraiswamy%2B" 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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 13</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 5 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Sep 1992 </div></div>
      
      
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