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<meta name="DC.Title" content="Craniosynostosis: diagnostic imaging with three-dimensional CT presentation." />
<meta name="DC.Date" content="1994-11-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="PURPOSE To measure diagnostic performance and preference of two three-dimensional CT reconstruction modalities (voxel-gradient and surface-projection) displayed two ways (conventional and unwrapped) in craniosynostosis confirmed by surgical inspection and histologic analysis of resected sutures.

METHODS High-resolution 2-mm contiguous CT sections were obtained and three-dimensional reconstruction images generated for 25 infants and children with skull deformities before surgical treatment of craniosynostosis. Two pediatric radiologists and two neuroradiologists first ranked images by their own preferences for diagnostic use. Then they diagnosed craniosynostosis from images presented in random order and blinded. The standard of reference was inspection during surgery and histologic evaluation of excised sutures. Finally, reviewers repeated their subjective preference tests.

RESULTS The least experienced radiologist had 100% sensitivity for all imaging modalities and specificities ranging from 43% to 83%. The two most experienced radiologists performed nearly identically, with sensitivities of 96% and specificities of 100%. After performing diagnostic tasks using all image types, all radiologists preferred conventional surface projections.

CONCLUSION Experienced readers can achieve nearly perfect diagnostic performance using the latest three-dimensional CT reconstruction images, making it a contribution to the diagnostic process. Although performance is nearly identical for all modalities, readers strongly prefer conventionally presented surface-projection images." />
<meta name="DC.Contributor" content="M W Vannier" />
<meta name="DC.Contributor" content="T K Pilgram" />
<meta name="DC.Contributor" content="J L Marsh" />
<meta name="DC.Contributor" content="B B Kraemer" />
<meta name="DC.Contributor" content="S C Rayne" />
<meta name="DC.Contributor" content="M H Gado" />
<meta name="DC.Contributor" content="C J Moran" />
<meta name="DC.Contributor" content="W H McAlister" />
<meta name="DC.Contributor" content="G D Shackelford" />
<meta name="DC.Contributor" content="R A Hardesty" />
<meta name="article:published_time" content="1994-11-01" />
<meta name="citation_title" content="Craniosynostosis: diagnostic imaging with three-dimensional CT presentation." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To measure diagnostic performance and preference of two three-dimensional CT reconstruction modalities (voxel-gradient and surface-projection) displayed two ways (conventional and unwrapped) in craniosynostosis confirmed by surgical inspection and histologic analysis of resected sutures.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;High-resolution 2-mm contiguous CT sections were obtained and three-dimensional reconstruction images generated for 25 infants and children with skull deformities before surgical treatment of craniosynostosis. Two pediatric radiologists and two neuroradiologists first ranked images by their own preferences for diagnostic use. Then they diagnosed craniosynostosis from images presented in random order and blinded. The standard of reference was inspection during surgery and histologic evaluation of excised sutures. Finally, reviewers repeated their subjective preference tests.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;The least experienced radiologist had 100% sensitivity for all imaging modalities and specificities ranging from 43% to 83%. The two most experienced radiologists performed nearly identically, with sensitivities of 96% and specificities of 100%. After performing diagnostic tasks using all image types, all radiologists preferred conventional surface projections.&lt;/p&gt;&lt;h3&gt;CONCLUSION&lt;/h3&gt;
&lt;p&gt;Experienced readers can achieve nearly perfect diagnostic performance using the latest three-dimensional CT reconstruction images, making it a contribution to the diagnostic process. Although performance is nearly identical for all modalities, readers strongly prefer conventionally presented surface-projection images.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_publication_date" content="1994/11/01" />
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<meta name="citation_author" content="M W Vannier" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="T K Pilgram" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="J L Marsh" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="B B Kraemer" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="S C Rayne" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="M H Gado" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="C J Moran" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="W H McAlister" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="citation_author" content="G D Shackelford" />
<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
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<meta name="citation_author_institution" content="Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110." />
<meta name="twitter:title" content="Craniosynostosis: diagnostic imaging with three-dimensional CT presentation." />
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<meta name="twitter:description" content="PURPOSE To measure diagnostic performance and preference of two three-dimensional CT reconstruction modalities (voxel-gradient and surface-projection) displayed two ways (conventional and unwrapped) in craniosynostosis confirmed by surgical inspection and histologic analysis of resected sutures.

METHODS High-resolution 2-mm contiguous CT sections were obtained and three-dimensional reconstruction images generated for 25 infants and children with skull deformities before surgical treatment of craniosynostosis. Two pediatric radiologists and two neuroradiologists first ranked images by their own preferences for diagnostic use. Then they diagnosed craniosynostosis from images presented in random order and blinded. The standard of reference was inspection during surgery and histologic evaluation of excised sutures. Finally, reviewers repeated their subjective preference tests.

RESULTS The least experienced radiologist had 100% sensitivity for all imaging modalities and specificities ranging from 43% to 83%. The two most experienced radiologists performed nearly identically, with sensitivities of 96% and specificities of 100%. After performing diagnostic tasks using all image types, all radiologists preferred conventional surface projections.

CONCLUSION Experienced readers can achieve nearly perfect diagnostic performance using the latest three-dimensional CT reconstruction images, making it a contribution to the diagnostic process. Although performance is nearly identical for all modalities, readers strongly prefer conventionally presented surface-projection images." />
<meta name="og-title" property="og:title" content="Craniosynostosis: diagnostic imaging with three-dimensional CT presentation." />
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<meta name="og-site-name" property="og:site_name" content="American Journal of Neuroradiology" />
<meta name="og-description" property="og:description" content="PURPOSE To measure diagnostic performance and preference of two three-dimensional CT reconstruction modalities (voxel-gradient and surface-projection) displayed two ways (conventional and unwrapped) in craniosynostosis confirmed by surgical inspection and histologic analysis of resected sutures.

METHODS High-resolution 2-mm contiguous CT sections were obtained and three-dimensional reconstruction images generated for 25 infants and children with skull deformities before surgical treatment of craniosynostosis. Two pediatric radiologists and two neuroradiologists first ranked images by their own preferences for diagnostic use. Then they diagnosed craniosynostosis from images presented in random order and blinded. The standard of reference was inspection during surgery and histologic evaluation of excised sutures. Finally, reviewers repeated their subjective preference tests.

RESULTS The least experienced radiologist had 100% sensitivity for all imaging modalities and specificities ranging from 43% to 83%. The two most experienced radiologists performed nearly identically, with sensitivities of 96% and specificities of 100%. After performing diagnostic tasks using all image types, all radiologists preferred conventional surface projections.

CONCLUSION Experienced readers can achieve nearly perfect diagnostic performance using the latest three-dimensional CT reconstruction images, making it a contribution to the diagnostic process. Although performance is nearly identical for all modalities, readers strongly prefer conventionally presented surface-projection images." />
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      <h1 class="highwire-cite-title" id="page-title">Craniosynostosis: diagnostic imaging with three-dimensional CT presentation.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">M W Vannier</span>, <span class="highwire-citation-author" data-delta="1">T K Pilgram</span>, <span class="highwire-citation-author" data-delta="2">J L Marsh</span>, <span class="highwire-citation-author" data-delta="3">B B Kraemer</span>, <span class="highwire-citation-author" data-delta="4">S C Rayne</span>, <span class="highwire-citation-author" data-delta="5">M H Gado</span>, <span class="highwire-citation-author" data-delta="6">C J Moran</span>, <span class="highwire-citation-author" data-delta="7">W H McAlister</span>, <span class="highwire-citation-author" data-delta="8">G D Shackelford</span> and <span class="highwire-citation-author" data-delta="9">R A Hardesty</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">November 1994,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1861-1869; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-6198--6193250610" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">M W Vannier </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=M%2BW%2BVannier%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Vannier%20MW&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AM%2BW%2BVannier%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">T K Pilgram </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, MO 63110.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=T%2BK%2BPilgram%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Pilgram%20TK&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on 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          <p id="p-1"><strong>PURPOSE</strong> To measure diagnostic performance and preference of two three-dimensional CT reconstruction modalities (voxel-gradient and surface-projection) displayed two ways (conventional and unwrapped) in craniosynostosis confirmed by surgical inspection and histologic analysis of resected sutures.</p>
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          <p id="p-2"><strong>METHODS</strong> High-resolution 2-mm contiguous CT sections were obtained and three-dimensional reconstruction images generated for 25 infants and children with skull deformities before surgical treatment of craniosynostosis. Two pediatric radiologists and two neuroradiologists first ranked images by their own preferences for diagnostic use. Then they diagnosed craniosynostosis from images presented in random order and blinded. The standard of reference was inspection during surgery and histologic evaluation of excised sutures. Finally, reviewers repeated their subjective preference tests.</p>
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          <p id="p-3"><strong>RESULTS</strong> The least experienced radiologist had 100% sensitivity for all imaging modalities and specificities ranging from 43% to 83%. The two most experienced radiologists performed nearly identically, with sensitivities of 96% and specificities of 100%. After performing diagnostic tasks using all image types, all radiologists preferred conventional surface projections.</p>
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          <p id="p-4"><strong>CONCLUSION</strong> Experienced readers can achieve nearly perfect diagnostic performance using the latest three-dimensional CT reconstruction images, making it a contribution to the diagnostic process. Although performance is nearly identical for all modalities, readers strongly prefer conventionally presented surface-projection images.</p>
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          <a href="/content/15/10" class="highwire-cite-linked-title" data-icon-position="" data-hide-link-title="0"><span class="highwire-cite-title">American Journal of Neuroradiology</span></a>      
      
        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 15</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 10 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Nov 1994 </div></div>
      
      
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Nov 1994, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1861-1869; </span></div>
  
  
  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Nov 1994, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(10) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">1861-1869; </span></div>
  
  
  
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