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<meta name="DC.Title" content="MR of fetal central nervous system abnormalities." />
<meta name="DC.Date" content="1994-03-01" />
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<meta name="DC.Description" content="PURPOSE To investigate whether MR can provide additional information on fetuses with central nervous system abnormalities as demonstrated by ultrasonography.

METHODS Fetal MR examinations were studied prospectively in 22 pregnant women whose fetuses showed evidence of anomalies on ultrasound performed in the High-Risk Obstetric Clinic.

RESULTS In 19 of 22 cases, postpartum confirmatory diagnoses were obtained by MR or CT examinations, autopsy, or surgery. In general, the image quality of MR is comparable with that of ultrasound. However, in six of 22 cases (27%), MR provided additional information that altered the ultrasound diagnosis; these included cases of infarction, diastematomyelia, normal hemimegalencephaly with early myelination, Dandy-Walker variant, and lipoma. All of these cases had postpartum confirmation. The additional information changed the treatment in three of six patients (no intervention or elective abortion).

CONCLUSIONS In certain situations MR can add valuable information to that obtained by sonography in the evaluation of the fetal central nervous system." />
<meta name="DC.Contributor" content="W T Yuh" />
<meta name="DC.Contributor" content="H D Nguyen" />
<meta name="DC.Contributor" content="D J Fisher" />
<meta name="DC.Contributor" content="E T Tali" />
<meta name="DC.Contributor" content="F Gao" />
<meta name="DC.Contributor" content="T M Simonson" />
<meta name="DC.Contributor" content="S C Kao" />
<meta name="DC.Contributor" content="C P Weiner" />
<meta name="article:published_time" content="1994-03-01" />
<meta name="citation_title" content="MR of fetal central nervous system abnormalities." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To investigate whether MR can provide additional information on fetuses with central nervous system abnormalities as demonstrated by ultrasonography.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;Fetal MR examinations were studied prospectively in 22 pregnant women whose fetuses showed evidence of anomalies on ultrasound performed in the High-Risk Obstetric Clinic.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;In 19 of 22 cases, postpartum confirmatory diagnoses were obtained by MR or CT examinations, autopsy, or surgery. In general, the image quality of MR is comparable with that of ultrasound. However, in six of 22 cases (27%), MR provided additional information that altered the ultrasound diagnosis; these included cases of infarction, diastematomyelia, normal hemimegalencephaly with early myelination, Dandy-Walker variant, and lipoma. All of these cases had postpartum confirmation. The additional information changed the treatment in three of six patients (no intervention or elective abortion).&lt;/p&gt;&lt;h3&gt;CONCLUSIONS&lt;/h3&gt;
&lt;p&gt;In certain situations MR can add valuable information to that obtained by sonography in the evaluation of the fetal central nervous system.&lt;/p&gt;" />
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<meta name="citation_author" content="W T Yuh" />
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<meta name="citation_author" content="H D Nguyen" />
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<meta name="citation_author" content="D J Fisher" />
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<meta name="citation_author" content="E T Tali" />
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<meta name="citation_author" content="F Gao" />
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<meta name="twitter:description" content="PURPOSE To investigate whether MR can provide additional information on fetuses with central nervous system abnormalities as demonstrated by ultrasonography.

METHODS Fetal MR examinations were studied prospectively in 22 pregnant women whose fetuses showed evidence of anomalies on ultrasound performed in the High-Risk Obstetric Clinic.

RESULTS In 19 of 22 cases, postpartum confirmatory diagnoses were obtained by MR or CT examinations, autopsy, or surgery. In general, the image quality of MR is comparable with that of ultrasound. However, in six of 22 cases (27%), MR provided additional information that altered the ultrasound diagnosis; these included cases of infarction, diastematomyelia, normal hemimegalencephaly with early myelination, Dandy-Walker variant, and lipoma. All of these cases had postpartum confirmation. The additional information changed the treatment in three of six patients (no intervention or elective abortion).

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<meta name="og-description" property="og:description" content="PURPOSE To investigate whether MR can provide additional information on fetuses with central nervous system abnormalities as demonstrated by ultrasonography.

METHODS Fetal MR examinations were studied prospectively in 22 pregnant women whose fetuses showed evidence of anomalies on ultrasound performed in the High-Risk Obstetric Clinic.

RESULTS In 19 of 22 cases, postpartum confirmatory diagnoses were obtained by MR or CT examinations, autopsy, or surgery. In general, the image quality of MR is comparable with that of ultrasound. However, in six of 22 cases (27%), MR provided additional information that altered the ultrasound diagnosis; these included cases of infarction, diastematomyelia, normal hemimegalencephaly with early myelination, Dandy-Walker variant, and lipoma. All of these cases had postpartum confirmation. The additional information changed the treatment in three of six patients (no intervention or elective abortion).

CONCLUSIONS In certain situations MR can add valuable information to that obtained by sonography in the evaluation of the fetal central nervous system." />
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      <h1 class="highwire-cite-title" id="page-title">MR of fetal central nervous system abnormalities.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">W T Yuh</span>, <span class="highwire-citation-author" data-delta="1">H D Nguyen</span>, <span class="highwire-citation-author" data-delta="2">D J Fisher</span>, <span class="highwire-citation-author" data-delta="3">E T Tali</span>, <span class="highwire-citation-author" data-delta="4">F Gao</span>, <span class="highwire-citation-author" data-delta="5">T M Simonson</span>, <span class="highwire-citation-author" data-delta="6">S C Kao</span> and <span class="highwire-citation-author" data-delta="7">C P Weiner</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">March 1994,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(3) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">459-464; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-5990--6822013939" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">W T Yuh </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Department of Radiology, University of Iowa College of Medicine, Iowa City 52242.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=W%2BT%2BYuh%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Yuh%20WT&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a href="/search/author1%3AW%2BT%2BYuh%2B" rel="nofollow" class="" 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          <div id="sec-1" class="subsection"><p id="p-1"><strong>PURPOSE</strong> To investigate whether MR can provide additional information on fetuses with central nervous system abnormalities as demonstrated by ultrasonography.</p></div>
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          <div id="sec-3" class="subsection"><p id="p-3"><strong>RESULTS</strong> In 19 of 22 cases, postpartum confirmatory diagnoses were obtained by MR or CT examinations, autopsy, or surgery. In general, the image quality of MR is comparable with that of ultrasound. However, in six of 22 cases (27%), MR provided additional information that altered the ultrasound diagnosis; these included cases of infarction, diastematomyelia, normal hemimegalencephaly with early myelination, Dandy-Walker variant, and lipoma. All of these cases had postpartum confirmation. The additional information changed the treatment in three of six patients (no intervention or elective abortion).</p></div>
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