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We agree with Drs. Vargas and Dietemann that T2-FSE is relatively a " />
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">F.H. Chokshi</span>, <span class="highwire-citation-author" data-delta="1">G. Sadigh</span>, <span class="highwire-citation-author" data-delta="2">W. Carpenter</span> and <span class="highwire-citation-author" data-delta="3">J.W. Allen</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">July 2017,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">38 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E50; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata">DOI: https://doi.org/10.3174/ajnr.A5202 </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-55129--671663664" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">F.H. Chokshi </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>a</span>Department of Radiology and Imaging Sciences, Division of Neuroradiology
Department of Biomedical Informatics</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=F.H.%2BChokshi%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Chokshi%20F&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AF.H.%2BChokshi%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-8476-9129" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for F.H. Chokshi</a></li></ul></div><div class="author-tooltip-1"><div class="author-tooltip-name">G. Sadigh </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>b</span>Department of Radiology and Imaging Sciences, Division of Neuroradiology</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=G.%2BSadigh%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Sadigh%20G&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AG.%2BSadigh%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0003-3233-1878" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for G. Sadigh</a></li></ul></div><div class="author-tooltip-2"><div class="author-tooltip-name">W. Carpenter </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>c</span>Department of Radiology and Imaging Sciences, Division of Musculoskeletal Radiology</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=W.%2BCarpenter%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Carpenter%20W&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AW.%2BCarpenter%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-0928-0374" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for W. Carpenter</a></li></ul></div><div class="author-tooltip-3"><div class="author-tooltip-name">J.W. Allen </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'><span class='nlm-sup'>d</span>Department of Radiology and Imaging Sciences, Division of Neuroradiology
Department of Neurology
Emory University School of Medicine
Atlanta, Georgia</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=J.W.%2BAllen%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=Allen%20J&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link"><a href="/search/author1%3AJ.W.%2BAllen%2B" rel="nofollow" class="" data-icon-position="" data-hide-link-title="0">Search for this author on this site</a></li><li class="author-orcid-link last"><a href="http://orcid.org/0000-0002-5274-1105" target="_blank" class="" data-icon-position="" data-hide-link-title="0">ORCID record for J.W. Allen</a></li></ul></div></div></div>  </div>

  
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    <div class="highwire-markup"><div xmlns="http://www.w3.org/1999/xhtml" data-highwire-cite-ref-tooltip-instance="highwire_reflinks_tooltip" class="content-block-markup" xmlns:xhtml="http://www.w3.org/1999/xhtml"><div class="article fulltext-view "><span class="highwire-journal-article-marker-start"></span><p id="p-1">We thank Drs. Vargas and Dietemann for their interest in our article “Diagnostic Quality of 3D T2-SPACE Compared with T2-FSE in the Evaluation of Cervical Spine MRI Anatomy”<sup><a id="xref-ref-1-1" class="xref-bibr" href="#ref-1">1</a></sup> and their thoughtful comments and suggestions.</p><p id="p-2">We agree with Drs. Vargas and Dietemann that T2-FSE is relatively a good sequence for the visualization of intrinsic spinal cord abnormality. However, to our knowledge, there have been no previous studies directly comparing its performance with T2-SPACE. The results of our study for the visualization of cord signal comparing the 2 sequences have been debated among our research team.</p><p id="p-3">We do agree that the visualization of intrinsic cord signal and pathology is suboptimal with the T2-SPACE sequence; however, this was not the primary focus of this study. Subsequent studies should evaluate the role of T2-SPACE imaging as an adjunct sequence to visualize or not visualize cord pathology. This, however, was outside of the scope of our project.</p><p id="p-4">Our study is not sufficient to provide guidance on the full range of imaging situations where T2-SPACE could be useful, but rather fills a void related to assessing the visualization of anatomic (not pathologic) cervical spine structures on MR imaging. We did not assess the diagnostic accuracy of T2-SPACE versus T2-FSE sequences in assessing degenerative changes, which would be a separate analysis and paper. We have also noticed the “false superficial siderosis” appearance in some, but not all, T2-SPACE images. We did not feel it was as pronounced as the authors' images show in their letter. With some training on visualizing T2-SPACE images, we believe that this appearance would not be problematic in clinical use.</p><p id="p-5">Future well-designed diagnostic accuracy and comparative effectiveness studies will better inform radiologists of the uses and limitations of T2-SPACE for C-spine imaging.</p><div class="section ref-list" id="ref-list-1"><h2 class="">Reference</h2><ol class="cit-list ref-use-labels"><li><span class="ref-label">1.</span><a class="rev-xref-ref" href="#xref-ref-1-1" title="View reference 1. in text" id="ref-1">↵</a><div class="cit ref-cit ref-journal" id="cit-38.7.E50.1" data-doi="10.3174/ajnr.A5080"><div class="cit-metadata"><ol class="cit-auth-list"><li>
</li><li><span class="cit-auth"><span class="cit-name-surname">Chokshi</span>  <span class="cit-name-given-names">FH</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Sadigh</span>  <span class="cit-name-given-names">G</span></span>, </li><li><span class="cit-auth"><span class="cit-name-surname">Carpenter</span>  <span class="cit-name-given-names">W</span></span>, <span class="cit-etal">et al</span></li></ol><cite>. <span class="cit-article-title">Diagnostic quality of 3D T2-SPACE compared with T2-FSE in the evaluation of cervical spine MRI anatomy</span>. <abbr class="cit-jnl-abbrev">AJNR Am J Neuroradiol</abbr> <span class="cit-pub-date">2017</span> 
<span class="cit-month">Feb</span> 
<span class="cit-day">2</span>. <span class="cit-comment">[Epub ahead of print]</span><span class="cit-pub-id-sep cit-pub-id-doi-sep"> </span><span class="cit-pub-id cit-pub-id-doi"><span class="cit-pub-id-scheme-doi">doi:</span>10.3174/ajnr.A5080</span><span class="cit-pub-id-sep cit-pub-id-pmid-sep"> </span><span class="cit-pub-id cit-pub-id-pmid"><span class="cit-pub-id-scheme-pmid">pmid:</span>28154126</span></cite></div><div class="cit-extra"><a href="/lookup/external-ref?access_num=10.3174/ajnr.A5080&amp;link_type=DOI" class="cit-ref-sprinkles cit-ref-sprinkles-doi cit-ref-sprinkles-crossref"><span>CrossRef</span></a><a href="/lookup/external-ref?access_num=28154126&amp;link_type=MED&amp;atom=%2Fajnr%2F38%2F7%2FE50.atom" class="cit-ref-sprinkles cit-ref-sprinkles-medline"><span>PubMed</span></a></div></div></li></ol></div><ul class="copyright-statement"><li class="fn" id="copyright-statement-1">© 2017 by American Journal of Neuroradiology</li></ul><span class="highwire-journal-article-marker-end"></span></div><span class="related-urls"></span></div></div>  </div>

  
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        	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-volume highwire-cite-metadata">Vol. 38</span>, <span  class="highwire-cite-metadata-issue highwire-cite-metadata">Issue 7 </span><div  class="highwire-cite-metadata-pubdate highwire-cite-metadata">1 Jul 2017 </div></div>
      
      
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    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0"><span class="nlm-given-names">F.H.</span> <span class="nlm-surname">Chokshi</span></span>, <span class="highwire-citation-author" data-delta="1"><span class="nlm-given-names">G.</span> <span class="nlm-surname">Sadigh</span></span>, <span class="highwire-citation-author" data-delta="2"><span class="nlm-given-names">W.</span> <span class="nlm-surname">Carpenter</span></span>, <span class="highwire-citation-author" data-delta="3"><span class="nlm-given-names">J.W.</span> <span class="nlm-surname">Allen</span></span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jul 2017, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">38 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E50; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A5202 </span></div>
  
  
  
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    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">Jul 2017, </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">38 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(7) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">E50; </span><span  class="highwire-cite-metadata-doi highwire-cite-metadata"><span class="label">DOI:</span> 10.3174/ajnr.A5202 </span></div>
  
  
  
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