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<meta name="DC.Title" content="Lack of age-related differences in temporal lobe volume of very healthy adults." />
<meta name="DC.Date" content="1994-04-01" />
<meta name="DC.Publisher" content="American Journal of Neuroradiology" />
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<meta name="DC.Description" content="PURPOSE To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age.

METHODS MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions.

RESULTS There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age.

CONCLUSION In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life." />
<meta name="DC.Contributor" content="C DeCarli" />
<meta name="DC.Contributor" content="D G Murphy" />
<meta name="DC.Contributor" content="J A Gillette" />
<meta name="DC.Contributor" content="J V Haxby" />
<meta name="DC.Contributor" content="D Teichberg" />
<meta name="DC.Contributor" content="M B Schapiro" />
<meta name="DC.Contributor" content="B Horwitz" />
<meta name="article:published_time" content="1994-04-01" />
<meta name="citation_title" content="Lack of age-related differences in temporal lobe volume of very healthy adults." />
<meta name="citation_abstract" lang="en" content="&lt;h3&gt;PURPOSE&lt;/h3&gt;
&lt;p&gt;To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age.&lt;/p&gt;&lt;h3&gt;METHODS&lt;/h3&gt;
&lt;p&gt;MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions.&lt;/p&gt;&lt;h3&gt;RESULTS&lt;/h3&gt;
&lt;p&gt;There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age.&lt;/p&gt;&lt;h3&gt;CONCLUSION&lt;/h3&gt;
&lt;p&gt;In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life.&lt;/p&gt;" />
<meta name="citation_journal_title" content="American Journal of Neuroradiology" />
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<meta name="citation_author" content="C DeCarli" />
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<meta name="citation_author" content="D G Murphy" />
<meta name="citation_author_institution" content="Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Md. 20892." />
<meta name="citation_author" content="J A Gillette" />
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<meta name="citation_author" content="J V Haxby" />
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<meta name="twitter:description" content="PURPOSE To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age.

METHODS MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions.

RESULTS There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age.

CONCLUSION In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life." />
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<meta name="og-description" property="og:description" content="PURPOSE To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age.

METHODS MR quantification of brain regions used image segmentation into cerebrospinal fluid and brain matter based on nonlinear modeling of pixel intensity distributions.

RESULTS There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age.

CONCLUSION In very healthy aging, the volume of the temporal lobes remains constant over the age range of human life." />
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    <div class="highwire-article-citation highwire-citation-type-highwire-article node6014--5" data-node-nid="6014" id="top-node-6014--654756303" data-pisa="ajnr;15/4/689" data-pisa-master="ajnr;15/4/689" data-apath="/ajnr/15/4/689.atom" data-hw-author-tooltip-instance="highwire_author_tooltip"><div class="highwire-cite highwire-cite-highwire-article highwire-citation-jcore-article-title-complete clearfix has-author-tooltip highwire-citation-highwire-article-top-a">
  
  
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      <h1 class="highwire-cite-title" id="page-title">Lack of age-related differences in temporal lobe volume of very healthy adults.</h1>  
    	<div class="highwire-cite-authors"><span  class="highwire-citation-authors"><span class="highwire-citation-author first" data-delta="0">C DeCarli</span>, <span class="highwire-citation-author" data-delta="1">D G Murphy</span>, <span class="highwire-citation-author" data-delta="2">J A Gillette</span>, <span class="highwire-citation-author" data-delta="3">J V Haxby</span>, <span class="highwire-citation-author" data-delta="4">D Teichberg</span>, <span class="highwire-citation-author" data-delta="5">M B Schapiro</span> and <span class="highwire-citation-author" data-delta="6">B Horwitz</span></span></div>
  
    	<div class="highwire-cite-metadata"><span  class="highwire-cite-metadata-journal highwire-cite-metadata">American Journal of Neuroradiology </span><span  class="highwire-cite-metadata-date highwire-cite-metadata">April 1994,  </span><span  class="highwire-cite-metadata-volume highwire-cite-metadata">15 </span><span  class="highwire-cite-metadata-issue highwire-cite-metadata">(4) </span><span  class="highwire-cite-metadata-pages highwire-cite-metadata">689-696; </span></div>
  
  
  
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<div id="hw-article-author-popups-top-node-6014--654756303" style="display: none;"><div class="author-tooltip-0"><div class="author-tooltip-name">C DeCarli </div><div class="author-tooltip-affiliation"><span class="author-tooltip-text"><div class='author-affiliation'>Laboratory of Neurosciences, National Institute on Aging, National Institutes of Health, Bethesda, Md. 20892.</div></span></div><ul class="author-tooltip-find-more"><li class="author-tooltip-gs-link first"><a href="/lookup/google-scholar?link_type=googlescholar&amp;gs_type=author&amp;author%5B0%5D=C%2BDeCarli%2B" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on Google Scholar</a></li><li class="author-tooltip-pubmed-link"><a href="/lookup/external-ref?access_num=DeCarli%20C&amp;link_type=AUTHORSEARCH" target="_blank" class="" data-icon-position="" data-hide-link-title="0">Find this author on PubMed</a></li><li class="author-site-search-link last"><a 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          <p id="p-1"><strong>PURPOSE</strong> To evaluate age-related differences in temporal and supratemporal brain regions in carefully selected, very healthy men 19 to 92 years of age.</p>
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          <p id="p-3"><strong>RESULTS</strong> There was a significant age-related decrease (approximately 1% per decade) of posterior frontal lobe volume, but not of temporal lobe volume. The mean volume of the right temporal lobe was significantly greater than the left, and this relation did not change with age.</p>
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      <div class="highwire-cite-title">Lack of age-related differences in temporal lobe volume of very healthy adults.</div>  
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      <div class="highwire-cite-title">Lack of age-related differences in temporal lobe volume of very healthy adults.</div>  
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